Innovating Biologics Discovery using the NonaHCAbFx Platform

  • The limitations of camelid nanobodies in bispecifics and the advantages of fully human HCAbs from Harbour Mice®.
  • A novel function-based screening platform for identifying CD19-targeting HCAbs using a CAR-Jurkat reporter system.
  • Discovery of fully human CD19 TCEs with superior cytotoxicity compared to reference molecules.