Why Attend the World Bispecific Summit?
The 17th World Bispecific Summit US brought together the industry's leading experts in antibody discovery, protein engineering, biology, analytical development, developability assessment, and early clinical development to solve the next generation of bispecific and multispecific drug development challenges.
With a focus on bispecific engineering, AI-enabled drug design, novel multispecific formats, co-stimulatory mechanisms, and developability strategies, the summit showcased the latest scientific advances shaping the future of multi-target therapeutics.
Here's a sample of just some of the sessions that generated excitement among the attendees:
AstraZeneca | Modular Generation of Multispecific Antibodies Using Protein Trans-Splicing
Attendees explored how AstraZeneca is leveraging protein trans-splicing to rapidly generate, screen, and optimise next-generation multispecific antibody formats.Amgen | Advancing Next-Generation TCEs with AI-Guided Drug Design
You would have discovered how AI-guided design is accelerating T-cell engager development and enhancing tumour selectivity.Formerly Bristol Myers Squibb | From Label to Launch: Formulation & CMC Lessons from FDA-Approved Bispecific & Multispecific Antibodies
Attendees gained valuable insights into the formulation, developability, and CMC strategies behind successful approved therapies.Xilio Therapeutics | Unlocking the Potential of Immuno-Oncology Using Masked Bi- & Multispecifics
You would have learned how masked bi- and multispecifics are being engineered to maximise efficacy while improving safety and tolerability.
As the field continues to evolve, success depends on overcoming mechanistic complexity, molecular differentiation, and clinical translation challenges. The 2026 agenda was purpose-built to help developers progress the next wave of bispecific and multispecific therapeutics from concept to clinic.
What Was New for 2026?
Attend the Deep Dive Seminar Day
Attendees learned about sophisticated molecular architecture, developability and stability-led engineering to derisk downstream development with Merck, Amgen and Crescent Biopharma
Uncover Novel Targets
You could have identified first-in-class opportunities and explored mechanistic rationale for different target combinations to maximize therapeutic efficacy with NextPoint Therapeutics, Oxford Biotherapeutics, Oblenio Bio and IN8Bio
Understand Novel Masking & Co-Stimulation Approaches
Attendees understood how novel masking and co-stimulation approaches drive therapeutic activity to improve therapeutic windows with Xilio Therapeutics, EvolveImmune Therapeutics and Rondo Therapeutics
Explore Complex Formats
You would have examined formats such as logic gated cell engagers and bispecific ADCs to overcome resistance, antigen escape and immune cell exhaustion with AstraZeneca, ImmuVia and ModeX Therapeutics
Modeling & Biomarker Strategies for Bispecifics
Attendees leveraged mechanistic modelling for dose selection and navigated future oncology and autoimmune directions for bispecifics using biomarker-led strategies with Takeda, Reverb Therapeutics and Amgen
Gather industry insights
Through discursive panel discussions, you could have covered the trends, data gaps, strengths and weaknesses of the space, as well as data submission package differences for autoimmune versus cancer indications
Brand-New Companies for 2026