Modular Generation of Multispecific Antibodies Using Protein Trans-Splicing
- Protein trans-splicing is a novel method for the generation of multispecific antibodies
- Spliced antibodies can be made in a wide array of formats and recapitulate the biophysical and functional properties of conventionally produced molecules
- This technology enables the discovery of binder pairs with unique biology by facilitating the high-throughput production and screening of combinatorial libraries of multispecific antibodies