Creating Conditionally Acting, Multifunctional Cell Engagers with Enhanced Target Selectivity & Reduced Toxicity Potential

  • Tuning antibody arms: optimizing for affinity and epitope recognition to instill cooperative, selective target binding
  • Integrating tuned effector modules to deliver target-selective, conditional cytokine receptor signalling
  • Combining and tuning antibody arms and effector payloads in the design and engineering of novel T cell engagers