Engineering Bispecific & Bipartopic ADCs for Dual-Target Engagement: Overcoming Design Challenges

  • Looking at the design of the Bipartopic JK06 to balance the target biology and payload safety and tolerability profile
  • Navigating the challenges of designing Bispecific and Bipartopic ADCs – exploring how ADCs can be engineered to recognize the antigens for both target cells, to then internalize in the cells
  • Investigating a case study of dual targeting with a Bispecific ADC to take away learnings on overcoming design challenges with dual-target engagement