Jijun Dong
Chief Scientific Officer Salubris Biotherapeutics
Seminars
Thursday 11th September 2025
Engineering Bispecific & Bipartopic ADCs for Dual-Target Engagement: Overcoming Design Challenges
11:30 am
- Looking at the design of the Bipartopic JK06 to balance the target biology and payload safety and tolerability profile
- Navigating the challenges of designing Bispecific and Bipartopic ADCs – exploring how ADCs can be engineered to recognize the antigens for both target cells, to then internalize in the cells
- Investigating a case study of dual targeting with a Bispecific ADC to take away learnings on overcoming design challenges with dual-target engagement
