Niko Kley
President & Chief Executive Officer Orionis Biosciences
Seminars
Wednesday 10th September 2025
Creating Conditionally Acting, Multifunctional Cell Engagers with Enhanced Target Selectivity & Reduced Toxicity Potential
9:00 am
- Tuning antibody arms: optimizing for affinity and epitope recognition to instill cooperative, selective target binding
- Integrating tuned effector modules to deliver target-selective, conditional cytokine receptor signalling
- Combining and tuning antibody arms and effector payloads in the design and engineering of novel T cell engagers
